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That said, as a result of a lack of serotogenic action I could take way more O-DSMT than I could an equivalent quantity of tramadol. I can certainly just take 500mg+ of O-DSMT in a day, which can be like 2500mg+ of tramadol (a dose I have never ever taken through each day).I began applying tramadol when I was an assistant to 1 Cargo driver in 2016.